Job DescriptionThe selected candidate will join the Grup de Recerca Neuromuscular de Badalona (GRENBA), an interdisciplinary team at the IGTP. GRENBA combines clinical, experimental, and computational approaches to advance research on rare neuromuscular diseases, with a particular focus on myotonic dystrophy type 1 (DM1).The fellow will contribute to our research program analyzing biological samples from DM1 patients enrolled in the DM1-Hub, Spain's national patient registry. At GRENBA, we apply long-read sequencing technologies to investigate the repetitive region associated with DM1, and we use bioinformatics and biostatistics to refine patient stratification and deepen understanding of disease pathophysiology.In addition, the candidate will design and implement innovative transcriptomic and metabolomic methodologies and multi-omics integration approaches to uncover novel mechanisms underlying DM1 and related neuromuscular disorders Main ResponsibilitiesThe research project will focus on the comprehensive characterization of the molecular pathophysiology of the patients within the DM1-Hub registry. The specific tasks and responsibilities include: Study of patient samples through long-read sequencing, focusing on the characterization of the DMPK region (expansion, variants, epigenetics and mosaicism).Integration of multi-omics data, including transcriptomic and metabolomic datasets, to investigate disease mechanisms and identify potential biomarkers. Development of proteomic protocols through ELISA and Western Blot for biomarker validation. Develop cell lines from patient samples for biomarker validation and preclinical drug testing. Maintain accurate experimental records and document results in a reproducible format. Collaboration with clinical and experimental teams to ensure translational relevance of the findings and contributions. Preparation of scientific publications, conference presentations, and reports derived from the project outcome EssentialQUALIFICATIONS AND EXPERIENCIE MSc (or equivalent) in Genetics, Biotechnology, Biomedicine, Biochemistry, Biology, Health Sciences, or closely related field. Have a minimum average grade of the academic record for undergraduate studies or of the equivalent degree equal to or greater than 8.5 (scale from 0 to 10). Competencies and skills: Communication, Teamwork and collaboration, Commitment, Proactivity, Integrity, Critical and Analytical thinking. High level of Spanish and English, written and spoken. Catalan is a plus. Advantageous: Hands-on experience with wet laboratory techniques, long-read sequencing, NGS, PCR, genomics, proteomics and/or transcriptomics. Hands-on experience in cell and tissue culture, aseptic techniques and sterile laboratory practices Scientific writing and presentation skills, as evidenced by peer-reviewed publications and conference contributions. International experience What We Offer The candidate can be only incorporated with an obtention of a FPU-2026, FI-AGAUR-2026 or similar. Pre-doctoral contract Full-time contract (1628h/year) Adaptable