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Vac_73_2025 - translational platform technician

Badalona
Carrerasresearch
Publicada el 6 septiembre
Descripción

Overview

The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conducting research and driving innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the ultimate goal of finding a cure for these diseases. Established in 2010, it has experienced exponential growth. The IJC is part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC). Additionally, IJC is integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) as an Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII).

The IJC\ 's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing access to cutting-edge scientific and technological facilities and community services. The IJC operates across six locations integrated into reference hospitals:
Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar, and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice.

We are seeking a Senior Translational Platform Technician in biomedicine to join the Core Facilities Area. This new platform will be established at IJC as soon as possible.

Main Responsibilities
* Write animal protocols for approval by the Institutional Animal Care and Use Committee.
* Design preclinical anti-tumor therapeutic efficacy studies / experiments in collaboration with IJC laboratory professionals.
* In vitro activities:
Basic cell culture and proliferation assays (new single agent or drug combination). In vitro organoid culture of primary tumors.
* In vivo activities:
Tumor implantation and transplantation (s.C., i.V., intrasplenic, retro-orbital, etc.), bone marrow transplantation.
* Pharmacokinetics, pharmacodynamics, and toxicity studies of new treatments (compounds, drugs, etc.).
* Single agent or drug combination treatments, immunotherapy (CAR-T, bispecific antibodies, etc.), gene therapy, hormonal studies, and supportive therapies like nutrition and pain management.
* Tumor monitoring / treatment follow-up using ultrasound, MRI, CT, and bioluminescent optical imaging (IVIS).
* Surgical procedures.
* Generate PDX mouse models (patient-derived xenografts).
* Manage genetically engineered mouse models (GEMM) (breeding, genotype analysis, etc.).
What We Need
* Bachelor’s degree in health sciences.
* Experience with pre-clinical studies.
* Experience in vivo techniques, animal models, PDX samples, pharmacology, advanced imaging, and drug development protocols is highly preferred.
* Experience in vitro techniques such as Flow Cytometry and organoid development.
* Ability to analyze and interpret data.
* Interest in translational research and collaborative team science.
* Excellent communication skills and motivation for high-impact research.
* Proficiency in English (speaking and writing).
* Ability to work independently and efficiently.
* Organized, self-motivated, and enthusiastic.
What We Offer
* Full-time contract (1623 hours / year).
* 1-year contract with potential extension ("Indefinido por actividades científico técnicas"), linked to the strategic plan supported by Severo Ochoa funds.
* Part of the aid #CEX -S, funded by MCIN / AEI.
* Measures for work-life balance:
flexible schedule, teleworking, 23 vacation days, and 9 personal days.
* Flexible remuneration options (including kindergarten support).
* Training and development opportunities.
* Work in a multinational, collaborative team.
* Work on a new strategic platform within the institute.
* Mixed basic and clinical research environment.
* Competitive salary, depending on experience.
* Stimulating scientific environment and network.
Deadline

Please submit your application by 1 September 2025.

Who We Are

The mission of the Josep Carreras Institute is to conduct research and drive innovation in leukemia and hematologic malignancies, aiming to find a cure. Our vision is to be a world-class research multicampus that improves patient outcomes through innovation and social responsibility.

HR Excellence

In 2019, IJC received the “Human Resources Excellence in Research Award” by the European Commission. Our policies align with the European Charter for Researchers and the Code of Conduct for Recruitment, emphasizing training, professional development, and mobility.

The Board of Trustees includes representatives from the Generalitat de Catalunya, University of Barcelona, Autonomous University of Barcelona, the City of Badalona, and the Jose Carreras International Leukaemia Foundation. The Catalan government provides annual funding, and the Foundation offers start-up and project funds. The IJC has an international advisory board and has received ERC and EU grants.

The IJC is an equal-opportunity employer. Qualified applicants are evaluated without regard to race, color, religion, sex, national origin, disability, or other protected characteristics.

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