Offer Description
The Pere Virgili Health Research Institute (IISPV) is an institution that integrates research in the field of biomedicine in the Camp de Tarragona and the Terres de l'Ebre regions. The IISPV is the instrument through which the university hospitals of both health regions (Joan XXIII University Hospital of Tarragona, Verge de la Cinta Hospital of Tortosa, Sant Joan University Hospital of Reus, Institut Pere Mata University Hospital of Reus) and the Universitat Rovira i Virgili have come together to bring together and manage biomedical research and innovation in the territory.
Description
There is a clear unmet clinical and technological need in the field of neonatal neurophysiology, particularly regarding amplitude-integrated electroencephalography (aEEG) monitoring and the accurate localization of scalp positions for neurophysiological and neuromodulatory procedures. This project addresses these gaps by generating new knowledge on neonatal brain monitoring, electrode design, and scalp-based localization methods. The proposal integrates device engineering, signal processing, computational neuroscience, and clinical neurophysiology to produce advances with high translational impact. The team builds on a strong trajectory including two granted international patents-aCUP-E (EP4138666B1) and EPlacement (EP4337085B1)-developed and clinically tested by both Principal Investigators of the project. Challenges revealed during their clinical validation revealed scientific gaps that now motivate this project's objectives and justify its oriented nature. Our group has recently developed a method using realistic head models to improve F3 localization. This method can be used on the webpage
General objectives
To develop and clinically validate a new software (MATLAB application) to assist clinicians to better diagnose from EEG/aEEG recordings and easy labelling recordings for research purposes; create a more sustainable and stable neonatal electrodes; and high-precision scalp localization methods in line with the “Salud” thematic priority.
Specific objectives
O1. Advanced EEG/aEEG analysis platform and brain maturation assessment
O2. Development and characterization of the aCUP-EcoStable electrode
O3. Improved cranial localization and 10-20 mapping using EPlacement and realistic head models
O4. Extension of the EPlacement-based cranial localization framework to rTMS coil positioning and neuromodulation
O5. Translation, implementation and impact assessment
References
- Fabregat-Sanjuan, A., Rodríguez-Ballabriga A., Rigo-Vidal A., Pàmies-Vilà R., Larrosa-Capaces S., Rius-Costa V., and Pascual-Rubio V. 2024. “Analysis of Electrode Performance on Amplitude Integrated Electroencephalography in Neonates: Evaluation of a New Electrode ACUP-E vs. Liquid Gel Electrodes.” Frontiers in Pediatrics 12. doi:
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- Mohedano, A; Fabregat-Sanjuan, A; Rius-Costa, V; Larrosa, S; Pascual-Rubio, V; Pàmies-Vilà, R;. Detección y Cuantificación del Sueño Tranquilo en Neonatos: Desarrollo de una Aplicación Interactiva para la Revisión Clínica de aEEG. XLIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB 2025).
- Fabregat-Sanjuan, A; Tomas Egea, A; Rius-Costa, V; Larrosa, S; Pascual-Rubio, V; Pàmies-Vilà, R;. Análisis de la Entropía Multiescala en la Maduración Cerebral Neonatal. XLIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB 2025).
- Rigo-Vidal, A.; Solé-Casals, J.; Pàmies-Vilà, R.; Fabregat-Sanjuan, A.; Pascual-Rubio, V. Análisis y clasificación automática de registros aEEG según la presencia y grado de patología. XLII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB 2024).
- Pàmies Vilà, R.; Craven-Bartle, F.; Rigo-Vidal, A.; Pascual-Rubio, V.; Fabregat-Sanjuan, A. Automated sleep cycle detection in newborns using amplitude-integrated electroencephalography. XLII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB 2024).
Application Process: All applications must be sent by email to, including your CV and a motivation letter.
Data límit: 20/02/2026
We look forward to receiving your applications.
Where to apply E-mail
a.fabregat@urv.cat
Requirements
Research Field Biological sciences Education Level Master Degree or equivalent
Internal Application form(s) needed
OT-URE-FOR-011 Model CRIDA rev 00 (Cat).pdf
English
(493.12 KB - PDF)
Additional Information
Work Location(s)
Number of offers available 1 Company/Institute Instituto de Investigación Sanitaria Pere y Virgili Country Spain Geofield
Contact State/Province
Tarragona City
TARRAGONA Website
Street
C/ ESCORXADOR S/N Postal Code
43003 E-Mail
rrhh@iispv.cat
STATUS: EXPIRED
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