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Junior technician – single cell genomics

Bioinformatics Barcelona
Publicada el 2 marzo
Descripción

Junior technician – single cell genomics

Deadline 19/03/2026

Centre / Institution: Center for Genomic Regulation

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

The Single Cell and Synthetic Genomics of Blood Formation lab (PI: Lars Velten) at CRG Barcelona is looking for a junior technician with initial experience in wet-lab molecular biology or genomics work, and a strong motivation to develop into a genomics bench science expert.

Blood formation is an essential, biomedically highly relevant, and complex process of cellular differentiation. Our group works on basic science projects on gene regulation in blood stem cells (e.g. Frömel et al., Cell 2025), and more translational projects in the context of acute myeloid leukemia (AML) and pre-leukemia (e.g. Beneyto-Calabuig et al., Cell Stem Cell 2023). Recently, we have developed EPI-Clone, a unique method to identify and characterize expanded stem cell clones independently of driver mutations and during physiological ageing (Scherer et al., Nature 2025). EPI-Clone enables a new look at blood clonality and has wide applications in studies of ageing, pre-leukemia, leukemia, and beyond. Our work on EPI-Clone was widely covered by the popular press (Le Monde, Financial Times, El País and others).

The successful candidate will work on translational applications of EPI-Clone. Specifically, they will support a senior technician in data generation. The position requires a strong study background in molecular biology, basic understanding of genomics and sequencing techniques, and a proven ability to work in the lab. It will allow you to develop a strong single-cell genomics skill set in a fast-paced research environment.

About the lab

My interdisciplinary group investigates the biology of hematopoietic stem cells using a combination of single cell genomics, genetic screens, and computational biology. We strive to develop novel genomic and bioinformatic tools to answer longstanding questions in the field. In particular, we cover two main research lines, a) Gene regulation in healthy hematopoiesis) and b) Clonal function in ageing and disease. The lab has been established in January 2020 and currently consists of seven members: Three PhD students, two postdocs and two senior technicians. We have received funding from the European Commission, the Spanish and German government, the Spanish Association Against Cancer and the European Hematology Association.

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