Bioinformatics Scientist – In Vivo CRISPR Screening
Contract: 6 months
Location: Remote.
Must be an EU Citizen with an active Limited company
Role Overview
My client is seeking a highly skilled Bioinformatics Scientist with strong expertise in in vivo CRISPR screening and CRISPR library design to support ongoing discovery and translational research initiatives. This is a 6-month contract role, working remotely within Spain, offering the opportunity to collaborate with multidisciplinary teams at the forefront of biomedical innovation.
Key Responsibilities
* Design and support in vivo CRISPR screening experiments, contributing to experimental strategy and downstream analytical planning.
* Collaborate on the design and generation of CRISPR libraries, ensuring high on-target efficiency and minimal off-target effects.
* Apply computational tools, pipelines, and statistical methods to process and interpret large-scale next-generation sequencing data.
* Analyse data from in vivo CRISPR screens to identify candidate gene targets and biologically meaningful signals.
* Validate, interpret, and clearly communicate results to support decision-making.
* Work closely with wet-lab and experimental biology teams to integrate bioinformatics insights into project pipelines.
Required Skills & Experience
* Strong background in bioinformatics, computational biology, or a related discipline .
* Demonstrated experience with in vivo CRISPR screening and CRISPR library design .
* Proficiency in analysing high-throughput sequencing data using computational and statistical approaches.
* Experience working with large datasets and developing or using bioinformatics pipelines.
* Ability to collaborate effectively within cross-functional, matrixed research teams .
* Excellent analytical thinking and clear scientific communication skills.
Desirable Experience
* Experience in pharmaceutical or biotech research environments .
* Familiarity with functional genomics, target discovery, or translational research workflows.