In vitro models are a key technology for the evaluation of novel biomaterials. 2D cell culture approaches are valuable for evaluating cytotoxicity but lack the complexity of native tissues. Therefore, there is a need to develop more advanced 3D models. Our research involves the development and characterization of in vitro tissue models based on organ‑on‑chip devices, electrospun membranes, and/or hydrogels for the study and treatment of different diseases, focusing on epithelial tissues (airways and skin) as well as bone and cardiac tissue.
Activities for this research support position involve the synthesis and application of materials to enable 3D cell culture, including co‑culture of different cell types, to support ongoing projects such as BIOMET4D and CARDIOBOOST. For example, biodegradable metals and actuator devices will be tested for effects on cytotoxicity and cell shape/alignment. The researcher will carry out chemical synthesis, materials characterization (microscopy, mechanical testing), electrospinning and 3D printing, and cell culture (including characterization of the viability, proliferation, and phenotype of the cells as well as morphology and organization).
The candidate should have a Bachelor’s degree or Master’s degree in Materials Science/Materials Engineering, Biomedical Engineering, Mechanical Engineering, Chemistry, Biomedical Sciences, or a related field. A good level of English (both oral and written) is mandatory; the working language of the Institute is English. The candidate should have experience from previous research in at least one of the following areas: cell culture (with preference for experience with skin or bone cell culture), materials processing (for example, electrospinning or 3D printing), materials characterization (biodegradation studies, ICP‑OES, electron microscopy, mechanical testing, etc.), organ‑on‑chip or microfluidic devices, confocal microscopy. Basic laboratory experience in cell culture and/or biosafety training as well as experience with data/image analysis is desirable. The candidate should have strong organizational and problem‑solving skills as well as the ability to work effectively in a multidisciplinary and international environment.
IMDEA Materials Institute is committed to equal opportunities, diversity and the promotion of a healthy work environment and work‑life balance. Female applicants are encouraged to apply.