Organisation/Company CIC biomaGUNE Department Research in Biomaterials Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Country Spain Application Deadline 7 Nov 2025 - 23:59 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 40 Offer Starting Date 1 Jan 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description
The successful candidate is expected to design, synthesise, and characterise small-molecule ligands, as well as develop radiolabeling routes with short-lived radioisotopes, including carbon-11 and/or fluorine-18, for positron emission tomography (PET) imaging. Beyond applying established methods, the candidate is expected to develop novel synthetic routes, explore new reactivity concepts, and implement innovative strategies in ligand design. Our research program covers: The development of imaging agents for fluorescence and PET Novel methodologies in organofluorine chemistry Greener and more sustainable synthetic routes for radiopharmaceutical development The specific focus of this PhD project is the development of high-affinity small molecules for targeting voltage-gated ion channels. Building on our previous work on fluorescent ligands for L-type calcium channels, our current focus is on the development of PET ligands for in vivo imaging of L-type calcium channel isoforms. The novel ligands will be evaluated in-house in tissue, cell and in vivo models to assess selectivity, binding properties and in vivo pharmacokinetics.
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