What's the project? Our client is a global powerhouse in the pharmaceutical and innovative medicine sector. They are currently pioneering a massive shift in how we treat complex, immune‐mediated diseases. Instead of just managing symptoms, the goal here is radical: disease state reversal.
By merging massive, cutting‐edge biological datasets (single‐cell genomics, proteomics, spatial transcriptomics) with advanced generative AI and machine learning, they are building a computational "time machine". The project focuses on predicting exactly how human cells will respond to specific genetic or chemical tweaks, allowing scientists to find the perfect therapeutic targets before anyone ever steps into a physical lab.
And your role in this? As a Senior Scientist in Multiomics Perturbation, you are the architect of this predictive framework. You'll bridge the gap between heavy‐data‐science and real‐world biology, taking complex data and turning it into therapies that will change lives. Your ultimate objective? Make target discovery faster, smarter, and precisely accurate for next‐generation treatments.
More specifically, you will:
Lead the design and tuning of AI/ML models that mix genetic and chemical screening data to predict how to flip the switch on diseased cells.
Build clever phenotype‐scoring systems to measure how effective cellular tweaks are.
Develop advanced computational methods to identify pathways and target combinations that stop disease.
Team up with experimental biologists and safety leads to ensure digital predictions translate into real‐world lab success.
Set up scalable, reproducible pipelines (such as Nextflow) and keep workflows running smoothly.
Ok, what should you bring? We're looking for a brilliant mind who loves solving biological puzzles with code. Here is your profile checklist:
The Must‐Haves (Your Superpowers) A Ph.D. in Bioinformatics, Computational Biology, Data Science, AI, or a quantitatively similar field.
2+ years of experience wrangling large‐scale multi‐omics data (single‐cell, transcriptomics, proteomics).
Hands‐on experience building AI/ML models, especially deep learning, representation learning, or transformer‐based methods applied to biological data.
Master‐level skills in high‐performance or cloud computing and reproducible workflow tools like Nextflow.
Ability to communicate both code and biology, translating complex data into stories for cross‐functional teammates.
The Nice‐to‐Haves (Your Extra Spice) Experience analyzing in‐vitro perturbation data (e.g., Perturb‐seq).
Solid understanding of immune‐mediated disease biology (bonus if knowledge of fibroblast pathobiology).
Familiarity with public omics databases and network/pathway analysis.
Interest in AI agents and agentic workflows.
Is that it? Not quite! The challenge involves handling incredibly complex, noisy, multimodal datasets and bringing harmony to the biological chaos using AI. It requires passion for innovation and creative grit.
The Salary:
Base Salary: €75,000 – €82,000 per year
Annual Bonus: Target of 12%
The Vibe & Benefits: The company culture balances a high‐impact research institute with a flexible, forward‐thinking tech environment. Package includes:
Premium health insurance and medical assistance
Comprehensive life insurance and a robust pension plan
Full access to an Employee Assistance Program (EAP)
Generous milestone celebrations (loyalty, wedding, and maternity awards)
27 days of vacation per year (25 standard + 2 extra days)
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