About the job
Mission
The Almirall Research team in Sant Feliu de Llobregat (Barcelona) is strengthening its core experimental department and is looking for a talented senior scientist with experience in in vivo pharmacology. The team is enabling the chemical and biologics pipeline from discovery up to preclinical development to treat dermatological indications and is responsible for delivery of high quality therapeutic lead candidates with a high potential for success in clinical development.
Tasks and Responsibilities
Key responsibilities include but are not limited to:
- Develop robust new in vivo humanized models in dermatological disease using best available technologies and equipment.
- Contribute to discovery and development projects for small molecules and antibody therapeutics by conducting in vivo efficacy, PK/PD studies utilizing syngeneic mouse and humanized models
- Maintain cell lines using standard cell culture techniques in support of in vivo studies.
- Use standard immunology techniques (MACS, FACS, ELISA) to support in vivo and ex vivo analysis of cells from animal tissues or human skin samples.
- Assay execution, maintaining the quality of assays, data analysis and publication.
- Active engagement across drug discovery activities and on project teams.
- Work in a highly cross-functional environment to align biologics and small molecules strategy from early project initiation.
- Write and or review technical and study reports
- Present scientific results at team and staff meetings
- Strong technical and computational abilities.
- Ability to work in a matrixed, collaborative environment with shared resources and effectively communicate within and across teams.
- Ability to work independently and prioritize work assignments.
Education & Experience
- Ph.D. and/or MSc. in relevant scientific area and minimally 4 years of hands-on in vivo pharmacology experience in academic or industry environment. Immuno-dermatology or dermato-oncology experience is a plus.
- EU license for designing procedures and projects on laboratory animal science or equivalent is a must.
- Proficiency in mouse handling and dosing (intradermal, intralesional, topical intraperitoneal, subcutaneous, intravenous, and oral gavage)
- Demonstrated ability to independently conduct dermatology mouse studies is a plus.
- Experience in developing and conducting syngeneic, xenograft, and humanized mouse models
- Excellent aseptic cell culture technique for handling human and murine primary cells and cancer cell lines
- Strong attention to detail.
- Excellent record-keeping abilities.
- Excellent interpersonal and communication skills.
- Demonstrated proficiency in the use of software tools to support data analysis (e. g., Prism, Flow Jo, Word, Excel, and Powerpoint)
- Ability to critically interpret and effectively present data
- Adaptability to shifting priorities and changing work assignments
Values
- Care
- Courage
- Innovation
- Simplicity
Why work with Almirall?
We are a people-centric company where employees are at their best, patients and customer are at the heart of every decision, and our focus and agility allow us to deliver greater impact for all.
Additionally, for the 17th year in a row, we have been certified as Top Employer Spain, and also Top Employer Germany for the first time.
This strengthens our commitment to create a unique work environment that helps our employees to develop their skills to fullest and grow both professionally and as individuals.
We are delighted to have a great team that is proactive, innovative, and eager to transform the world of people with skin conditions.
We are proud of each one of our employees, their development, and growth: they are the success of the company.
Our purpose
Transform the patients' world by helping them realize their hopes & dreams for a healthy life".
Our values
- Care: we listen & empathize, we value diverse perspectives & backgrounds and we help each other succeed.
- Courage: we challenge the status quo, we take full ownership and we learn from our success & failures.
- Innovation: we put the patient and customer at the center, we create novel solutions and we empower entrepreneurial mindsets.
- Simplicity: we act decisively and avoid over-analysis, we understand why before we act and we are agile & keep things simple.
At Almirall, it’s all about people!
#wearealmirall
Summary
- Location: SANT FELIU DE LLOBREGAT
- Type: Full time